Izumi Yasaka's runaway car was on its way to the Public Safety Bureau building when it was reported just before it hit the building. Izumi, a counselor at Sanctuary, a latent criminal isolation and rehabilitation center, recently fled her job. Before Inspectors Mika Shimotsuki and Akane Tsunemori had a chance to question the suspect, the facility suddenly asks for Izumi to be brought back. The Inspectors comply, taking this to be a direct command from the Chief and the Sanctuary board, but they insist that Izumi be personally taken back. Tsunemori plans to carry out additional research alongside the Bureau team. Inspector Shimotsuki is now granted the chance she has been yearning for—to serve as the primary inspector investigating a significant case. Shimotsuki and her group of Enforcers are followed in this case as they learn the truth about Sanctuary.