In the year 200X, World War III began. Special bombs destroyed parts of cities such as Tokyo, leaving decimation in their wake. Decades later, ground zero in Tokyo – an isolated section known as the Black Spot – remains an enigma. Its residents known as Needless possess strange powers such as the ability to control fire or telekinesis, and are constantly hunted down by Simeon, a large pharmaceutical company with sinister motives and Needless of their own to do their bidding. Young Cruz is part of a resistance to fight against Simeon and its Needless figurehead leader, Adam Arclight; but after the resistance is brutally killed by Simeon’s minions, he finds himself saved by a motley crew: Professor Gido, scantily-clad Eve and badass Blade. Together, the gang fends off Simeon’s attacks and tries to discover the truth behind the corporation’s actions. What is Simeon really after, and why do they desperately want to find Fragments?